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Week 9

Viruses

Basic Viral Structure and Replication

  • Know the structure of bacteriophages as well as animal viruses.
  • Be able to identify and explain the steps in viral replication.
  • Know the difference between lysogenic and lytic viral cycles.

Bacteriophages vs. Animal Viruses

  • Be able to compare and contrast the infective cycles of bacteriophages and animal viruses.
  • Be able to explain the steps of the infective cycle of an animal virus; use HIV as a specific example.

Effects of Infection by a Virus

  • Be able to explain the possible outcomes of infection by a virus:
    • Disease process (as exemplified by influenza, herpes, smallpox, or rabies).
    • Teratogenesis
    • Cancer
  • Be able to discuss in detail the influenza virus:
    • Its structure and the role of this structure in infection as well as genetic drift and shift.
    • Why the 1918 influenza pandemic was so devastating;
    • What its reservoir is and how it goes from infecting birds to infecting humans;
    • What steps are taken to prevent a pandemic like the 1918 one;
    • The dangers of avian flu.
  • How can viral infection lead to secondary bacterial infections?

Viral Diseases –Lectures are online in Vancko Hall

  • Small Pox, Influenza, Rabies, Herpes
  • Also Avian Influenza!

Viral “Activity” as Obligate Intracellular Parasites

Know the ideas about the origin of viruses as outlined in your text.

  • In what ways are they living?  …nonliving?

Reading:

  • Be sure to read the introduction to viruses in your text (pp.271-276)
  • Read up on Herpesviruses in your text:  pp. 627-632
  • Read about influenza in your text pp. 660-665.

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